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Differential pH-dependent cellular uptake pathways among foamy viruses elucidated using dual-colored fluorescent particles

BACKGROUND: It is thought that foamy viruses (FVs) enter host cells via endocytosis because all FV glycoproteins examined display pH-dependent fusion activities. Only the prototype FV (PFV) glycoprotein has also significant fusion activity at neutral pH, suggesting that its uptake mechanism may devi...

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Detalles Bibliográficos
Autores principales: Stirnnagel, Kristin, Schupp, Dorothee, Dupont, Aurélie, Kudryavtsev, Volodymyr, Reh, Juliane, Müllers, Erik, Lamb, Don C, Lindemann, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495412/
https://www.ncbi.nlm.nih.gov/pubmed/22935135
http://dx.doi.org/10.1186/1742-4690-9-71