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Medulla oblongata transcriptome changes during presymptomatic natural scrapie and their association with prion-related lesions

BACKGROUND: The pathogenesis of natural scrapie and other prion diseases is still poorly understood. Determining the variations in the transcriptome in the early phases of the disease might clarify some of the molecular mechanisms of the prion-induced pathology and allow for the development of new b...

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Detalles Bibliográficos
Autores principales: Filali, Hicham, Martin-Burriel, Inmaculada, Harders, Frank, Varona, Luis, Serrano, Carmen, Acín, Cristina, Badiola, Juan J, Bossers, Alex, Bolea, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495657/
https://www.ncbi.nlm.nih.gov/pubmed/22897917
http://dx.doi.org/10.1186/1471-2164-13-399