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Dose-dependent expression of neuronal injury markers during experimental osteoarthritis induced by monoiodoacetate in the rat
BACKGROUND: It was recently reported that the mono-iodoacetate (MIA) experimental model of osteoarthritis (OA) courses with changes of neurons innervating the affected joints that are commonly interpreted as a neuronal response to axonal injury. To better characterize these changes, we evaluated the...
Autores principales: | Ferreira-Gomes, Joana, Adães, Sara, Sousa, Raquel Meireles, Mendonça, Marcelo, Castro-Lopes, José Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495674/ https://www.ncbi.nlm.nih.gov/pubmed/22769424 http://dx.doi.org/10.1186/1744-8069-8-50 |
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