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Genome-scale modeling using flux ratio constraints to enable metabolic engineering of clostridial metabolism in silico

BACKGROUND: Genome-scale metabolic networks and flux models are an effective platform for linking an organism genotype to its phenotype. However, few modeling approaches offer predictive capabilities to evaluate potential metabolic engineering strategies in silico. RESULTS: A new method called “flux...

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Detalles Bibliográficos
Autores principales:	McAnulty, Michael J, Yen, Jiun Y, Freedman, Benjamin G, Senger, Ryan S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495714/ https://www.ncbi.nlm.nih.gov/pubmed/22583864 http://dx.doi.org/10.1186/1752-0509-6-42

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