2D, 3D-QSAR and docking studies of 1,2,3-thiadiazole thioacetanilides analogues as potent HIV-1 non-nucleoside reverse transcriptase inhibitors

BACKGROUND: The discovery of clinically relevant inhibitors of HIV-RT for antiviral therapy has proven to be a challenging task. To identify novel and potent HIV-RT inhibitors, the quantitative structure–activity relationship (QSAR) approach became very useful and largely widespread technique forlig...

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Detalles Bibliográficos
Autores principales: Jain, Shailesh V, Ghate, Manjunath, Bhadoriya, Kamlendra S, Bari, Sanjaykumar B, Chaudhari, Amar, Borse, Jayshri S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495901/
https://www.ncbi.nlm.nih.gov/pubmed/22691718
http://dx.doi.org/10.1186/2191-2858-2-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495901/
https://www.ncbi.nlm.nih.gov/pubmed/22691718
http://dx.doi.org/10.1186/2191-2858-2-22

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