Inhibition of 5′-UTR RNA Conformational Switching in HIV-1 Using Antisense PNAs

BACKGROUND: The genome of retroviruses, including HIV-1, is packaged as two homologous (+) strand RNA molecules, noncovalently associated close to their 5′-end in a region called dimer linkage structure (DLS). Retroviral HIV-1 genomic RNAs dimerize through complex interactions between dimerization i...

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Detalles Bibliográficos
Autores principales: Parkash, Braham, Ranjan, Atul, Tiwari, Vinod, Gupta, Sharad Kumar, Kaur, Navrinder, Tandon, Vibha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495914/
https://www.ncbi.nlm.nih.gov/pubmed/23152893
http://dx.doi.org/10.1371/journal.pone.0049310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495914/
https://www.ncbi.nlm.nih.gov/pubmed/23152893
http://dx.doi.org/10.1371/journal.pone.0049310

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