Cyclic Stretch Induces Cell Reorientation on Substrates by Destabilizing Catch Bonds in Focal Adhesions

A minimal model of cellular mechanosensing system that consists of a single stress fiber adhering on a substrate via two focal adhesions made of catch bonds is adopted to investigate the phenomena of cell reorientation on substrates induced by an applied uniaxial cyclic stretch. The model indicates...

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Detalles Bibliográficos
Autores principales: Chen, Bin, Kemkemer, Ralf, Deibler, Martin, Spatz, Joachim, Gao, Huajian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495948/
https://www.ncbi.nlm.nih.gov/pubmed/23152769
http://dx.doi.org/10.1371/journal.pone.0048346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495948/
https://www.ncbi.nlm.nih.gov/pubmed/23152769
http://dx.doi.org/10.1371/journal.pone.0048346

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