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Neural Progenitor Cells Regulate Microglia Functions and Activity States

We observed that mouse neural progenitor cells (NPCs) have a secretory protein profile distinct from other brain cells and modulate microglial activation, proliferation, and phagocytosis in culture and in vivo. NPC-derived vascular endothelial growth factor was necessary and sufficient to exert at l...

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Detalles Bibliográficos
Autores principales: Mosher, Kira I., Andres, Robert H., Fukuhara, Takeshi, Bieri, Gregor, Hasegawa-Moriyama, Maiko, He, Yingbo, Guzman, Raphael, Wyss-Coray, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495979/
https://www.ncbi.nlm.nih.gov/pubmed/23086334
http://dx.doi.org/10.1038/nn.3233