Cargando…
Steps solidifying a role for SEPT9 in breast cancer suggest that greater strides are needed
Septins comprise a conserved family of GTPase proteins. Of these, human SEPT9 has been widely implicated in cancers of epithelial origin, including breast cancer, as well as leukemia. In a previous issue of Breast Cancer Research, Connolly and colleagues present compelling data further supporting a...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496112/ https://www.ncbi.nlm.nih.gov/pubmed/22236777 http://dx.doi.org/10.1186/bcr3056 |
_version_ | 1782249601950023680 |
---|---|
author | Stanbery, Laura Petty, Elizabeth M |
author_facet | Stanbery, Laura Petty, Elizabeth M |
author_sort | Stanbery, Laura |
collection | PubMed |
description | Septins comprise a conserved family of GTPase proteins. Of these, human SEPT9 has been widely implicated in cancers of epithelial origin, including breast cancer, as well as leukemia. In a previous issue of Breast Cancer Research, Connolly and colleagues present compelling data further supporting a role for SEPT9 isoforms in early breast cancer development as well as evidence suggesting that cellular localization patterns of SEPT9 isoforms may contribute to oncogenesis. |
format | Online Article Text |
id | pubmed-3496112 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-34961122012-11-14 Steps solidifying a role for SEPT9 in breast cancer suggest that greater strides are needed Stanbery, Laura Petty, Elizabeth M Breast Cancer Res Editorial Septins comprise a conserved family of GTPase proteins. Of these, human SEPT9 has been widely implicated in cancers of epithelial origin, including breast cancer, as well as leukemia. In a previous issue of Breast Cancer Research, Connolly and colleagues present compelling data further supporting a role for SEPT9 isoforms in early breast cancer development as well as evidence suggesting that cellular localization patterns of SEPT9 isoforms may contribute to oncogenesis. BioMed Central 2012 2012-01-09 /pmc/articles/PMC3496112/ /pubmed/22236777 http://dx.doi.org/10.1186/bcr3056 Text en Copyright ©2012 BioMed Central Ltd |
spellingShingle | Editorial Stanbery, Laura Petty, Elizabeth M Steps solidifying a role for SEPT9 in breast cancer suggest that greater strides are needed |
title | Steps solidifying a role for SEPT9 in breast cancer suggest that greater strides are needed |
title_full | Steps solidifying a role for SEPT9 in breast cancer suggest that greater strides are needed |
title_fullStr | Steps solidifying a role for SEPT9 in breast cancer suggest that greater strides are needed |
title_full_unstemmed | Steps solidifying a role for SEPT9 in breast cancer suggest that greater strides are needed |
title_short | Steps solidifying a role for SEPT9 in breast cancer suggest that greater strides are needed |
title_sort | steps solidifying a role for sept9 in breast cancer suggest that greater strides are needed |
topic | Editorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496112/ https://www.ncbi.nlm.nih.gov/pubmed/22236777 http://dx.doi.org/10.1186/bcr3056 |
work_keys_str_mv | AT stanberylaura stepssolidifyingaroleforsept9inbreastcancersuggestthatgreaterstridesareneeded AT pettyelizabethm stepssolidifyingaroleforsept9inbreastcancersuggestthatgreaterstridesareneeded |