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Evidence that GTP-binding domain but not catalytic domain of transglutaminase 2 is essential for epithelial-to-mesenchymal transition in mammary epithelial cells

INTRODUCTION: The expression of proinflammatory protein tissue transglutaminase 2 (TG2) is frequently upregulated in multiple cancer cell types. However, the exact role of TG2 in cancer cells is not well-understood. We recently initiated studies to determine the significance of TG2 in cancer cells a...

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Detalles Bibliográficos
Autores principales:	Kumar, Anupam, Xu, Jia, Sung, Bokyung, Kumar, Santosh, Yu, Dihua, Aggarwal, Bharat B, Mehta, Kapil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496119/ https://www.ncbi.nlm.nih.gov/pubmed/22225906 http://dx.doi.org/10.1186/bcr3085

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