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Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer

INTRODUCTION: Overexpression of the oxygen-responsive transcription factor hypoxia-inducible factor 1α (HIF-1α) correlates with poor prognosis in breast cancer patients. The mouse mammary tumor virus polyoma virus middle T (MMTV-PyMT) mouse is a widely utilized preclinical mouse model that resembles...

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Detalles Bibliográficos
Autores principales:	Schwab, Luciana P, Peacock, Danielle L, Majumdar, Debeshi, Ingels, Jesse F, Jensen, Laura C, Smith, Keisha D, Cushing, Richard C, Seagroves, Tiffany N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496121/ https://www.ncbi.nlm.nih.gov/pubmed/22225988 http://dx.doi.org/10.1186/bcr3087

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