Cargando…
Extra-binomial variation approach for analysis of pooled DNA sequencing data
Motivation: The invention of next-generation sequencing technology has made it possible to study the rare variants that are more likely to pinpoint causal disease genes. To make such experiments financially viable, DNA samples from several subjects are often pooled before sequencing. This induces la...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496343/ https://www.ncbi.nlm.nih.gov/pubmed/22976083 http://dx.doi.org/10.1093/bioinformatics/bts553 |