Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages

Inflammatory neovascularization, such as choroidal neovascularization (CNV), occur in the presence of Notch expressing macrophages. DLL4s anti-angiogenic effect on endothelial cells (EC) has been widely recognized, but its influence on Notch signaling on macrophages and its overall effect in inflamm...

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Detalles Bibliográficos
Autores principales: Camelo, Serge, Raoul, William, Lavalette, Sophie, Calippe, Bertrand, Cristofaro, Brunella, Levy, Olivier, Houssier, Marianne, Sulpice, Eric, Jonet, Laurent, Klein, Christophe, Devevre, Estelle, Thuret, Gilles, Duarte, Antonio, Eichmann, Anne, Leconte, Laurence, Guillonneau, Xavier, Sennlaub, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496480/
https://www.ncbi.nlm.nih.gov/pubmed/22869002
http://dx.doi.org/10.1007/s10456-012-9290-0

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