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Positron emission tomography imaging of tumor angiogenesis and monitoring of antiangiogenic efficacy using the novel tetrameric peptide probe (64)Cu-cyclam-RAFT-c(-RGDfK-)(4)
(64)Cu-cyclam-RAFT-c(-RGDfK-)(4) is a novel multimeric positron emission tomography (PET) probe for α(V)β(3) integrin imaging. Its uptake and α(V)β(3) expression in tumors showed a linear correlation. Since α(V)β(3) integrin is strongly expressed on activated endothelial cells during angiogenesis, w...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496517/ https://www.ncbi.nlm.nih.gov/pubmed/22644563 http://dx.doi.org/10.1007/s10456-012-9281-1 |