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Positron emission tomography imaging of tumor angiogenesis and monitoring of antiangiogenic efficacy using the novel tetrameric peptide probe (64)Cu-cyclam-RAFT-c(-RGDfK-)(4)

(64)Cu-cyclam-RAFT-c(-RGDfK-)(4) is a novel multimeric positron emission tomography (PET) probe for α(V)β(3) integrin imaging. Its uptake and α(V)β(3) expression in tumors showed a linear correlation. Since α(V)β(3) integrin is strongly expressed on activated endothelial cells during angiogenesis, w...

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Detalles Bibliográficos
Autores principales:	Jin, Zhao-Hui, Furukawa, Takako, Claron, Michael, Boturyn, Didier, Coll, Jean-Luc, Fukumura, Toshimitsu, Fujibayashi, Yasuhisa, Dumy, Pascal, Saga, Tsuneo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2012
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496517/ https://www.ncbi.nlm.nih.gov/pubmed/22644563 http://dx.doi.org/10.1007/s10456-012-9281-1

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