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Regulation of in vitro human T cell development through interleukin-7 deprivation and anti-CD3 stimulation

BACKGROUND: The role of IL-7 and pre-TCR signaling during T cell development has been well characterized in murine but not in human system. We and others have reported that human BM hematopoietic progenitor cells (HPCs) display poor proliferation, inefficient double negative (DN) to double positive...

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Detalles Bibliográficos
Autores principales:	Patel, Ekta S, Okada, Starlyn, Hachey, Kevin, Yang, Li-jun, Durum, Scott K, Moreb, Jan S, Chang, Lung-Ji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496569/ https://www.ncbi.nlm.nih.gov/pubmed/22897934 http://dx.doi.org/10.1186/1471-2172-13-46

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