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CD8+ and CD4+ cytotoxic T cell escape mutations precede breakthrough SIVmac239 viremia in an elite controller

BACKGROUND: Virus-specific T cells are critical components in the containment of immunodeficiency virus infections. While the protective role of CD8+ T cells is well established by studies of CD8+ T cell-mediated viral escape, it remains unknown if CD4+ T cells can also impose sufficient selective p...

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Detalles Bibliográficos
Autores principales:	Burwitz, Benjamin J, Giraldo-Vela, Juan Pablo, Reed, Jason, Newman, Laura P, Bean, Alexander T, Nimityongskul, Francesca A, Castrovinci, Philip A, Maness, Nicholas J, Leon, Enrique J, Rudersdorf, Richard, Sacha, Jonah B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496649/ https://www.ncbi.nlm.nih.gov/pubmed/23131037 http://dx.doi.org/10.1186/1742-4690-9-91

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