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Role of toll-like receptor 4 on the immune escape of human oral squamous cell carcinoma and resistance of cisplatin-induced apoptosis

BACKGROUND: Toll-like receptor 4 (TLR4) is expressed on immune cells as a sensor that recognizes lipopolysaccharide (LPS), a microbial conserved component. It has recently been determined that the expression of TLR4 is also found in various types of tumor cells. Cisplatin is a widely used chemothera...

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Detalles Bibliográficos
Autores principales: Sun, Zujun, Luo, Qingqiong, Ye, Dongxia, Chen, Wantao, Chen, Fuxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496658/
https://www.ncbi.nlm.nih.gov/pubmed/22583829
http://dx.doi.org/10.1186/1476-4598-11-33