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Sphere Culture of Murine Lung Cancer Cell Lines Are Enriched with Cancer Initiating Cells

Cancer initiating cells (CICs) represent a unique cell population essential for the maintenance and growth of tumors. Most in vivo studies of CICs utilize human tumor xenografts in immunodeficient mice. These models provide limited information on the interaction of CICs with the host immune system a...

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Detalles Bibliográficos
Autores principales: Morrison, Brian J., Steel, Jason C., Morris, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496706/
https://www.ncbi.nlm.nih.gov/pubmed/23152931
http://dx.doi.org/10.1371/journal.pone.0049752