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Frequent Epigenetic Silencing of the Folate-Metabolising Gene Cystathionine-Beta-Synthase in Gastrointestinal Cancer

BACKGROUND: Both gastric and colorectal cancers (CRC) are the most frequently occurring malignancies worldwide with the overall survival of these patients remains unsatisfied. Identification of tumor suppressor genes (TSG) silenced by promoter CpG methylation uncovers mechanisms of tumorigenesis and...

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Detalles Bibliográficos
Autores principales:	Zhao, Hong, Li, Qinshan, Wang, Jian, Su, Xianwei, Ng, Ka Man, Qiu, Tian, Shan, Ling, Ling, Yun, Wang, Linfang, Cai, Jianqiang, Ying, Jianming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496708/ https://www.ncbi.nlm.nih.gov/pubmed/23152928 http://dx.doi.org/10.1371/journal.pone.0049683

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