17-AAG Kills Intracellular Leishmania amazonensis while Reducing Inflammatory Responses in Infected Macrophages

BACKGROUND: Leishmaniasis is a neglected endemic disease with a broad spectrum of clinical manifestations. Pentavalent antimonials have been the treatment of choice for the past 70 years and, due to the emergence of resistant cases, the efficacy of these drugs has come under scrutiny. Second-line dr...

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Detalles Bibliográficos
Autores principales: Petersen, Antonio Luis de Oliveira Almeida, Guedes, Carlos Eduardo Sampaio, Versoza, Carolina Leite, Lima, José Geraldo Bomfim, de Freitas, Luiz Antônio Rodrigues, Borges, Valéria Matos, Veras, Patrícia Sampaio Tavares
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496716/
https://www.ncbi.nlm.nih.gov/pubmed/23152914
http://dx.doi.org/10.1371/journal.pone.0049496

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