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Inhibition of Cyclooxygenase-2 Reduces Hypothalamic Excitation in Rats with Adriamycin-Induced Heart Failure

BACKGROUND: The paraventricular nucleus (PVN) of the hypothalamus plays an important role in the progression of heart failure (HF). We investigated whether cyclooxygenase-2 (COX-2) inhibition in the PVN attenuates the activities of sympathetic nervous system (SNS) and renin-angiotensin system (RAS)...

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Detalles Bibliográficos
Autores principales:	Zheng, Min, Kang, Yu-Ming, Liu, Wei, Zang, Wei-Jin, Bao, Cui-Yu, Qin, Da-Nian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496718/ https://www.ncbi.nlm.nih.gov/pubmed/23152801 http://dx.doi.org/10.1371/journal.pone.0048771

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