Polyethyleneimine is a potent mucosal adjuvant for glycoproteins with innate and adaptive immune activating properties

There are no mucosal adjuvant formulations licensed for human use, despite protection against many mucosally-transmitted infections probably requiring immunity at the site of pathogen entry(1). Polyethyleneimines (PEI) are organic polycations used as nucleic acid transfection reagents in vitro, and...

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Detalles Bibliográficos
Autores principales: Wegmann, Frank, Gartlan, Kate H, Harandi, Ali M, Brinckmann, Sarah A, Coccia, Margherita, Hillson, William R, Kok, Wai Ling, Cole, Suzanne, Ho, Ling-Pei, Lambe, Teresa, Puthia, Manoj, Svanborg, Catharina, Scherer, Erin M, Krashias, George, Williams, Adam, Blattman, Joseph N, Greenberg, Philip D, Flavell, Richard A, Moghaddam, Amin E, Sheppard, Neil C, Sattentau, Quentin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496939/
https://www.ncbi.nlm.nih.gov/pubmed/22922673
http://dx.doi.org/10.1038/nbt.2344

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