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Sepia Ink Oligopeptide Induces Apoptosis in Prostate Cancer Cell Lines via Caspase-3 Activation and Elevation of Bax/Bcl-2 Ratio

Sepia ink oligopeptide (SIO) is a tripeptide extracted from Sepia ink. To test the hypothesis that SIO inhibits prostate cancer by inducing apoptosis, the effects of SIO on the proliferation of three human prostate cancer cell lines were examined using a CCK-8 assay. SIO significantly inhibited the...

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Detalles Bibliográficos
Autores principales: Huang, Fangfang, Yang, Zuisu, Yu, Di, Wang, Jiabin, Li, Rong, Ding, Guofang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497014/
https://www.ncbi.nlm.nih.gov/pubmed/23170075
http://dx.doi.org/10.3390/md10102153