Cargando…

Antioxidant and Anti-Protease Activities of Diazepinomicin from the Sponge-Associated Micromonospora Strain RV115

Diazepinomicin is a dibenzodiazepine alkaloid with an unusual structure among the known microbial metabolites discovered so far. Diazepinomicin was isolated from the marine sponge-associated strain Micromonospora sp. RV115 and was identified by spectroscopic analysis and by comparison to literature...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abdelmohsen, Usama Ramadan, Szesny, Matthias, Othman, Eman Maher, Schirmeister, Tanja, Grond, Stephanie, Stopper, Helga, Hentschel, Ute
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497017/ https://www.ncbi.nlm.nih.gov/pubmed/23170078 http://dx.doi.org/10.3390/md10102208

Ejemplares similares

Identification of Plakortide E from the Caribbean Sponge Plakortis halichondroides as a Trypanocidal Protease Inhibitor using Bioactivity-Guided Fractionation
por: Oli, Swarna, et al.
Publicado: (2014)

Isolation of Petrocidin A, a New Cytotoxic Cyclic Dipeptide from the Marine Sponge-Derived Bacterium Streptomyces sp. SBT348
por: Cheng, Cheng, et al.
Publicado: (2017)

Marine Sponge-Derived Streptomyces sp. SBT343 Extract Inhibits Staphylococcal Biofilm Formation
por: Balasubramanian, Srikkanth, et al.
Publicado: (2017)

Production of Induced Secondary Metabolites by a Co-Culture of Sponge-Associated Actinomycetes, Actinokineospora sp. EG49 and Nocardiopsis sp. RV163
por: Dashti, Yousef, et al.
Publicado: (2014)

Mining Genomes of Three Marine Sponge-Associated Actinobacterial Isolates for Secondary Metabolism
por: Horn, Hannes, et al.
Publicado: (2015)

Anti-protease and Immunomodulatory Activities of Bacteria Associated with Caribbean Sponges
por: Tabares, Paula, et al.
Publicado: (2011)

Identification of the protease inhibitor miraziridine A in the Red sea sponge Theonella swinhoei
por: Tabares, Paula, et al.
Publicado: (2012)

Actinomycetes from Red Sea Sponges: Sources for Chemical and Phylogenetic Diversity
por: Abdelmohsen, Usama Ramadan, et al.
Publicado: (2014)

Unusual N-Prenylation in Diazepinomicin Biosynthesis: The Farnesylation of a Benzodiazepine Substrate Is Catalyzed by a New Member of the ABBA Prenyltransferase Superfamily
por: Bonitz, Tobias, et al.
Publicado: (2013)

Draft Genome Sequence of the Antitrypanosomally Active Sponge-Associated Bacterium Actinokineospora sp. Strain EG49
por: Harjes, Janno, et al.
Publicado: (2014)

Induction of Antibacterial Metabolites by Co-Cultivation of Two Red-Sea-Sponge-Associated Actinomycetes Micromonospora sp. UR56 and Actinokinespora sp. EG49
por: S. Hifnawy, Mohamed, et al.
Publicado: (2020)

The genus Micromonospora as a model microorganism for bioactive natural product discovery
por: Hifnawy, Mohamed S., et al.
Publicado: (2020)

Biodiversity, Anti-Trypanosomal Activity Screening, and Metabolomic Profiling of Actinomycetes Isolated from Mediterranean Sponges
por: Cheng, Cheng, et al.
Publicado: (2015)

Isolation, Phylogenetic Analysis and Anti-infective Activity Screening of Marine Sponge-Associated Actinomycetes
por: Abdelmohsen, Usama Ramadan, et al.
Publicado: (2010)

Dereplication Strategies for Targeted Isolation of New Antitrypanosomal Actinosporins A and B from a Marine Sponge Associated-Actinokineospora sp. EG49
por: Abdelmohsen, Usama Ramadan, et al.
Publicado: (2014)

Defining the Species Micromonospora saelicesensis and Micromonospora noduli Under the Framework of Genomics
por: Riesco, Raúl, et al.
Publicado: (2018)

An Enrichment of CRISPR and Other Defense-Related Features in Marine Sponge-Associated Microbial Metagenomes
por: Horn, Hannes, et al.
Publicado: (2016)

Bioactive natural products from marine sponges belonging to family Hymedesmiidae
por: Elgoud Said, Asmaa Abo, et al.
Publicado: (2021)

Effects of Resveratrol, Lovastatin and the mTOR-Inhibitor RAD-001 on Insulin-Induced Genomic Damage In Vitro
por: Awad, Eman, et al.
Publicado: (2017)

Exploring Micromonospora as Phocoenamicins Producers
por: Kokkini, Maria, et al.
Publicado: (2022)

Draft Genome Sequence of Micromonospora sp. Strain WMMA1996, a Marine Sponge-Associated Bacterium
por: Braun, Doug R., et al.
Publicado: (2018)

A Glossary for Chemical Approaches towards Unlocking the Trove of Metabolic Treasures in Actinomycetes
por: Zhang, Jianye, et al.
Publicado: (2021)

Natural Product Repertoire of the Genus Amphimedon
por: Shady, Nourhan Hisham, et al.
Publicado: (2018)

The Plant Hormone Cytokinin Confers Protection against Oxidative Stress in Mammalian Cells
por: Othman, Eman M., et al.
Publicado: (2016)

A New Micromonospora Strain with Antibiotic Activity Isolated from the Microbiome of a Mid-Atlantic Deep-Sea Sponge
por: Back, Catherine R., et al.
Publicado: (2021)

New Tetromycin Derivatives with Anti-Trypanosomal and Protease Inhibitory Activities
por: Pimentel-Elardo, Sheila M., et al.
Publicado: (2011)

New bioactive metabolites from the elicited marine sponge-derived bacterium Actinokineospora spheciospongiae sp. nov.
por: Tawfike, Ahmed, et al.
Publicado: (2019)

Emerging Sponge Models of Animal-Microbe Symbioses
por: Pita, Lucia, et al.
Publicado: (2016)

Network Pharmacological Analysis of the Red Sea Sponge Hyrtios erectus Extract to Reveal Anticancer Efficacy of Corresponding Loaded Niosomes
por: Abou-Taleb, Heba A., et al.
Publicado: (2022)

Bioactive Natural Products of Marine Sponges from the Genus Hyrtios
por: Shady, Nourhan Hisham, et al.
Publicado: (2017)

Endophytic Actinobacteria and the Interaction of Micromonospora and Nitrogen Fixing Plants
por: Trujillo, Martha E., et al.
Publicado: (2015)

Deciphering Genomes: Genetic Signatures of Plant-Associated Micromonospora
por: Riesco, Raúl, et al.
Publicado: (2022)

New Cytotoxic Cyclic Peptide from the Marine Sponge-Associated Nocardiopsis sp. UR67
por: Ibrahim, Alyaa Hatem, et al.
Publicado: (2018)

Hepatitis C Virus NS3 Protease and Helicase Inhibitors from Red Sea Sponge (Amphimedon) Species in Green Synthesized Silver Nanoparticles Assisted by in Silico Modeling and Metabolic Profiling
por: Shady, Nourhan Hisham, et al.
Publicado: (2020)

Marine natural products from sponges (Porifera) of the order Dictyoceratida (2013 to 2019); a promising source for drug discovery
por: Abdelaleem, Enas Reda, et al.
Publicado: (2020)

The Occurrence of Bioactive Micromonosporae in Aquatic Habitats of the Sunshine Coast in Australia
por: Eccleston, Glen P., et al.
Publicado: (2008)

Nematicidal Metabolites from the Actinomycete Micromonospora sp. WH06
por: Ran, Yuan, et al.
Publicado: (2022)

Draft Genome Sequences of “Candidatus Synechococcus spongiarum,” Cyanobacterial Symbionts of the Mediterranean Sponge Aplysina aerophoba
por: Slaby, Beate M., et al.
Publicado: (2017)

Maternal provisioning of an obligate symbiont in a sponge
por: Carrier, Tyler J., et al.
Publicado: (2023)

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
por: Owis, Asmaa I., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_83lsgn1t736vk2dd0te4746mmf