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Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c)
The dinoflagellate Prorocentrum belizeanum is responsible for the production of several toxins involved in the red tide phenomenon known as Diarrhetic Shellfish Poisoning (DSP). In this paper we report on the biosynthetic origin of an okadaic acid water-soluble ester derivative, DTX5c, on the basis...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497019/ https://www.ncbi.nlm.nih.gov/pubmed/23170080 http://dx.doi.org/10.3390/md10102234 |
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author | Vilches, Tamara S. Norte, Manuel Daranas, Antonio Hernández Fernández, José J. |
author_facet | Vilches, Tamara S. Norte, Manuel Daranas, Antonio Hernández Fernández, José J. |
author_sort | Vilches, Tamara S. |
collection | PubMed |
description | The dinoflagellate Prorocentrum belizeanum is responsible for the production of several toxins involved in the red tide phenomenon known as Diarrhetic Shellfish Poisoning (DSP). In this paper we report on the biosynthetic origin of an okadaic acid water-soluble ester derivative, DTX5c, on the basis of the spectroscopical analysis of (13)C enriched samples obtained by addition of labelled sodium [l-(13)C], [2-(13)C] acetate to artificial cultures of this dinoflagellate. |
format | Online Article Text |
id | pubmed-3497019 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-34970192012-11-20 Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c) Vilches, Tamara S. Norte, Manuel Daranas, Antonio Hernández Fernández, José J. Mar Drugs Article The dinoflagellate Prorocentrum belizeanum is responsible for the production of several toxins involved in the red tide phenomenon known as Diarrhetic Shellfish Poisoning (DSP). In this paper we report on the biosynthetic origin of an okadaic acid water-soluble ester derivative, DTX5c, on the basis of the spectroscopical analysis of (13)C enriched samples obtained by addition of labelled sodium [l-(13)C], [2-(13)C] acetate to artificial cultures of this dinoflagellate. MDPI 2012-10-12 /pmc/articles/PMC3497019/ /pubmed/23170080 http://dx.doi.org/10.3390/md10102234 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Article Vilches, Tamara S. Norte, Manuel Daranas, Antonio Hernández Fernández, José J. Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c) |
title | Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c) |
title_full | Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c) |
title_fullStr | Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c) |
title_full_unstemmed | Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c) |
title_short | Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c) |
title_sort | biosynthetic studies on water-soluble derivative 5c (dtx5c) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497019/ https://www.ncbi.nlm.nih.gov/pubmed/23170080 http://dx.doi.org/10.3390/md10102234 |
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