Cargando…

Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c)

The dinoflagellate Prorocentrum belizeanum is responsible for the production of several toxins involved in the red tide phenomenon known as Diarrhetic Shellfish Poisoning (DSP). In this paper we report on the biosynthetic origin of an okadaic acid water-soluble ester derivative, DTX5c, on the basis...

Descripción completa

Detalles Bibliográficos
Autores principales: Vilches, Tamara S., Norte, Manuel, Daranas, Antonio Hernández, Fernández, José J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497019/
https://www.ncbi.nlm.nih.gov/pubmed/23170080
http://dx.doi.org/10.3390/md10102234
_version_ 1782249704521728000
author Vilches, Tamara S.
Norte, Manuel
Daranas, Antonio Hernández
Fernández, José J.
author_facet Vilches, Tamara S.
Norte, Manuel
Daranas, Antonio Hernández
Fernández, José J.
author_sort Vilches, Tamara S.
collection PubMed
description The dinoflagellate Prorocentrum belizeanum is responsible for the production of several toxins involved in the red tide phenomenon known as Diarrhetic Shellfish Poisoning (DSP). In this paper we report on the biosynthetic origin of an okadaic acid water-soluble ester derivative, DTX5c, on the basis of the spectroscopical analysis of (13)C enriched samples obtained by addition of labelled sodium [l-(13)C], [2-(13)C] acetate to artificial cultures of this dinoflagellate.
format Online
Article
Text
id pubmed-3497019
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-34970192012-11-20 Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c) Vilches, Tamara S. Norte, Manuel Daranas, Antonio Hernández Fernández, José J. Mar Drugs Article The dinoflagellate Prorocentrum belizeanum is responsible for the production of several toxins involved in the red tide phenomenon known as Diarrhetic Shellfish Poisoning (DSP). In this paper we report on the biosynthetic origin of an okadaic acid water-soluble ester derivative, DTX5c, on the basis of the spectroscopical analysis of (13)C enriched samples obtained by addition of labelled sodium [l-(13)C], [2-(13)C] acetate to artificial cultures of this dinoflagellate. MDPI 2012-10-12 /pmc/articles/PMC3497019/ /pubmed/23170080 http://dx.doi.org/10.3390/md10102234 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Vilches, Tamara S.
Norte, Manuel
Daranas, Antonio Hernández
Fernández, José J.
Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c)
title Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c)
title_full Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c)
title_fullStr Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c)
title_full_unstemmed Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c)
title_short Biosynthetic Studies on Water-Soluble Derivative 5c (DTX5c)
title_sort biosynthetic studies on water-soluble derivative 5c (dtx5c)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497019/
https://www.ncbi.nlm.nih.gov/pubmed/23170080
http://dx.doi.org/10.3390/md10102234
work_keys_str_mv AT vilchestamaras biosyntheticstudiesonwatersolublederivative5cdtx5c
AT nortemanuel biosyntheticstudiesonwatersolublederivative5cdtx5c
AT daranasantoniohernandez biosyntheticstudiesonwatersolublederivative5cdtx5c
AT fernandezjosej biosyntheticstudiesonwatersolublederivative5cdtx5c