Bafilomycin A1 activates HIF-dependent signalling in human colon cancer cells via mitochondrial uncoupling

Mitochondrial uncoupling is implicated in many patho(physiological) states. Using confocal live cell imaging and an optical O(2) sensing technique, we show that moderate uncoupling of the mitochondria with plecomacrolide Baf (bafilomycin A1) causes partial depolarization of the mitochondria and deep...

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Detalles Bibliográficos
Autores principales: Zhdanov, Alexander V., Dmitriev, Ruslan I., Papkovsky, Dmitri B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497721/
https://www.ncbi.nlm.nih.gov/pubmed/22943412
http://dx.doi.org/10.1042/BSR20120085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497721/
https://www.ncbi.nlm.nih.gov/pubmed/22943412
http://dx.doi.org/10.1042/BSR20120085

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