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Specific (12)C(β)D(2)(12)C(γ)D(2)S(13)C(ε)HD(2) Isotopomer Labeling of Methionine To Characterize Protein Dynamics by (1)H and (13)C NMR Relaxation Dispersion

[Image: see text] Protein dynamics on the micro- to millisecond time scale is increasingly found to be critical for biological function, as demonstrated by numerous NMR relaxation dispersion studies. Methyl groups are excellent probes of protein interactions and dynamics because of their favorable N...

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Detalles Bibliográficos
Autores principales: Weininger, Ulrich, Liu, Zhihong, McIntyre, Deane D., Vogel, Hans J., Akke, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497853/
https://www.ncbi.nlm.nih.gov/pubmed/23106551
http://dx.doi.org/10.1021/ja309294u

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