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Nucleotide exchange factors: Kinetic analyses and the rationale for studying kinetics of GEFs
Exchange factors are enzymes that catalyze the exchange of GTP for GDP on guanine nucleotide binding proteins. Progress in understanding the molecular basis of action and the cellular functions of these enzymes has largely come from structural determinations (e.g., crystal structures) and studying e...
Autores principales: | Northup, John K., Jian, Xiaoying, Randazzo, Paul A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498072/ https://www.ncbi.nlm.nih.gov/pubmed/23181196 http://dx.doi.org/10.4161/cl.21627 |
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