Cargando…

Cullin-3 and the endocytic system: New functions of ubiquitination for endosome maturation

Cullin-RING-ligases (CRLs) comprise the largest class of multisubunit E3 ubiquitin ligases, which regulate a broad range of cellular processes. Cullin3 (Cul3) recently emerged as an important regulator of intracellular trafficking, in particular secretion and endosome maturation. Here we summarize a...

Descripción completa

Detalles Bibliográficos
Autores principales: Hubner, Michaela, Peter, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498076/
https://www.ncbi.nlm.nih.gov/pubmed/23739092
http://dx.doi.org/10.4161/cl.20372
_version_ 1782249782265249792
author Hubner, Michaela
Peter, Matthias
author_facet Hubner, Michaela
Peter, Matthias
author_sort Hubner, Michaela
collection PubMed
description Cullin-RING-ligases (CRLs) comprise the largest class of multisubunit E3 ubiquitin ligases, which regulate a broad range of cellular processes. Cullin3 (Cul3) recently emerged as an important regulator of intracellular trafficking, in particular secretion and endosome maturation. Here we summarize and discuss possible functions and substrates of Cul3 in the endocytic system.
format Online
Article
Text
id pubmed-3498076
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Landes Bioscience
record_format MEDLINE/PubMed
spelling pubmed-34980762012-11-23 Cullin-3 and the endocytic system: New functions of ubiquitination for endosome maturation Hubner, Michaela Peter, Matthias Cell Logist Article Addendum Cullin-RING-ligases (CRLs) comprise the largest class of multisubunit E3 ubiquitin ligases, which regulate a broad range of cellular processes. Cullin3 (Cul3) recently emerged as an important regulator of intracellular trafficking, in particular secretion and endosome maturation. Here we summarize and discuss possible functions and substrates of Cul3 in the endocytic system. Landes Bioscience 2012-07-01 /pmc/articles/PMC3498076/ /pubmed/23739092 http://dx.doi.org/10.4161/cl.20372 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Article Addendum
Hubner, Michaela
Peter, Matthias
Cullin-3 and the endocytic system: New functions of ubiquitination for endosome maturation
title Cullin-3 and the endocytic system: New functions of ubiquitination for endosome maturation
title_full Cullin-3 and the endocytic system: New functions of ubiquitination for endosome maturation
title_fullStr Cullin-3 and the endocytic system: New functions of ubiquitination for endosome maturation
title_full_unstemmed Cullin-3 and the endocytic system: New functions of ubiquitination for endosome maturation
title_short Cullin-3 and the endocytic system: New functions of ubiquitination for endosome maturation
title_sort cullin-3 and the endocytic system: new functions of ubiquitination for endosome maturation
topic Article Addendum
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498076/
https://www.ncbi.nlm.nih.gov/pubmed/23739092
http://dx.doi.org/10.4161/cl.20372
work_keys_str_mv AT hubnermichaela cullin3andtheendocyticsystemnewfunctionsofubiquitinationforendosomematuration
AT petermatthias cullin3andtheendocyticsystemnewfunctionsofubiquitinationforendosomematuration