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Cullin-3 and the endocytic system: New functions of ubiquitination for endosome maturation
Cullin-RING-ligases (CRLs) comprise the largest class of multisubunit E3 ubiquitin ligases, which regulate a broad range of cellular processes. Cullin3 (Cul3) recently emerged as an important regulator of intracellular trafficking, in particular secretion and endosome maturation. Here we summarize a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498076/ https://www.ncbi.nlm.nih.gov/pubmed/23739092 http://dx.doi.org/10.4161/cl.20372 |
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author | Hubner, Michaela Peter, Matthias |
author_facet | Hubner, Michaela Peter, Matthias |
author_sort | Hubner, Michaela |
collection | PubMed |
description | Cullin-RING-ligases (CRLs) comprise the largest class of multisubunit E3 ubiquitin ligases, which regulate a broad range of cellular processes. Cullin3 (Cul3) recently emerged as an important regulator of intracellular trafficking, in particular secretion and endosome maturation. Here we summarize and discuss possible functions and substrates of Cul3 in the endocytic system. |
format | Online Article Text |
id | pubmed-3498076 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Landes Bioscience |
record_format | MEDLINE/PubMed |
spelling | pubmed-34980762012-11-23 Cullin-3 and the endocytic system: New functions of ubiquitination for endosome maturation Hubner, Michaela Peter, Matthias Cell Logist Article Addendum Cullin-RING-ligases (CRLs) comprise the largest class of multisubunit E3 ubiquitin ligases, which regulate a broad range of cellular processes. Cullin3 (Cul3) recently emerged as an important regulator of intracellular trafficking, in particular secretion and endosome maturation. Here we summarize and discuss possible functions and substrates of Cul3 in the endocytic system. Landes Bioscience 2012-07-01 /pmc/articles/PMC3498076/ /pubmed/23739092 http://dx.doi.org/10.4161/cl.20372 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Article Addendum Hubner, Michaela Peter, Matthias Cullin-3 and the endocytic system: New functions of ubiquitination for endosome maturation |
title | Cullin-3 and the endocytic system: New functions of ubiquitination for endosome maturation |
title_full | Cullin-3 and the endocytic system: New functions of ubiquitination for endosome maturation |
title_fullStr | Cullin-3 and the endocytic system: New functions of ubiquitination for endosome maturation |
title_full_unstemmed | Cullin-3 and the endocytic system: New functions of ubiquitination for endosome maturation |
title_short | Cullin-3 and the endocytic system: New functions of ubiquitination for endosome maturation |
title_sort | cullin-3 and the endocytic system: new functions of ubiquitination for endosome maturation |
topic | Article Addendum |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498076/ https://www.ncbi.nlm.nih.gov/pubmed/23739092 http://dx.doi.org/10.4161/cl.20372 |
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