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Autoinactivation of the Stargazin–AMPA Receptor Complex: Subunit-Dependency and Independence from Physical Dissociation
Agonist responses and channel kinetics of native α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors are modulated by transmembrane accessory proteins. Stargazin, the prototypical accessory protein, decreases desensitization and increases agonist potency at AMPA receptors. Further...
Autores principales: | Semenov, Artur, Möykkynen, Tommi, Coleman, Sarah K., Korpi, Esa R., Keinänen, Kari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498123/ https://www.ncbi.nlm.nih.gov/pubmed/23166629 http://dx.doi.org/10.1371/journal.pone.0049282 |
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