IFN Regulatory Factor 8 Is a Key Constitutive Determinant of the Morphological and Molecular Properties of Microglia in the CNS

IFN regulatory factor (IRF) 8 is a transcription factor that has a key role in the cellular response to IFN-γ and is pivotal in myeloid cell differentiation. Whether IRF8 plays a role in the development and function of microglia, the tissue-resident myeloid cells of the brain, is unknown. Here, we s...

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Detalles Bibliográficos
Autores principales: Minten, Carsten, Terry, Rachael, Deffrasnes, Celine, King, Nicholas J. C., Campbell, Iain L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498170/
https://www.ncbi.nlm.nih.gov/pubmed/23166780
http://dx.doi.org/10.1371/journal.pone.0049851

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