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Recurrent Mesalazine-Induced Myopericarditis in a Patient with Ulcerative Colitis

Inflammatory bowel disease (IBD) is considered as a dysregulated immune mediated disease. Pericarditis in IBD is a very rare disease both as an extra-intestinal manifestation of IBD and an adverse reaction of therapeutic drug for IBD such as mesalazine or sulfasalazine. A 26-year-old IBD male patien...

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Detalles Bibliográficos
Autores principales: Park, Eun Hye, Kim, Byung Jin, Huh, Jung Kwon, Jeong, Eun Haeng, Lee, Sang Hyuk, Bang, Ki Bae, Seol, Ji Soo, Sung, Joo Wook, Kim, Bum Soo, Kang, Jin Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Echocardiography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498314/
https://www.ncbi.nlm.nih.gov/pubmed/23185660
http://dx.doi.org/10.4250/jcu.2012.20.3.154
Descripción
Sumario:Inflammatory bowel disease (IBD) is considered as a dysregulated immune mediated disease. Pericarditis in IBD is a very rare disease both as an extra-intestinal manifestation of IBD and an adverse reaction of therapeutic drug for IBD such as mesalazine or sulfasalazine. A 26-year-old IBD male patient who had been taking mesalazine regularly for about 1 month was referred to our hospital because of fever, chest discomfort, and abnormal electrocardiographic findings. The patients was diagnosed as acute myopericarditis, and recovered after cessation of mesalazine using steroid and aspirin. When mesalazine was re-medicated some days after discharge, he suffered from myopericarditis again. Subsequently, myopericarditis was resolved just after cessation of mesalazine again. These findings suggest that the development of myopericarditis is caused by mesalazine.