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Isomeric Mono-, Di-, and Tri-Bromobenzo-1H-Triazoles as Inhibitors of Human Protein Kinase CK2α

To further clarify the role of the individual bromine atoms of 4,5,6,7-tetrabromotriazole (TBBt), a relatively selective inhibitor of protein kinase CK2, we have examined the inhibition (IC(50)) of human CK2α by the two mono-, the four di-, and the two tri- bromobenzotriazoles relative to that of TB...

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Detalles Bibliográficos
Autores principales: Wąsik, Romualda, Wińska, Patrycja, Poznański, Jarosław, Shugar, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498355/
https://www.ncbi.nlm.nih.gov/pubmed/23155426
http://dx.doi.org/10.1371/journal.pone.0048898