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Angiotensin-Converting Enzyme 2 Over-Expression in the Central Nervous System Reduces Angiotensin-II-Mediated Cardiac Hypertrophy

Angiotensin-converting enzyme type 2 (ACE2) has been shown to be an important member of the renin angiotensin system. Previously, we observed that central ACE2 reduces the development of hypertension following chronic angiotensin II (Ang-II) infusion in syn-hACE2 transgenic (SA) mice, in which the h...

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Detalles Bibliográficos
Autores principales: Feng, Yumei, Hans, Chetan, McIlwain, Elizabeth, Varner, Kurt J., Lazartigues, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498357/
https://www.ncbi.nlm.nih.gov/pubmed/23155428
http://dx.doi.org/10.1371/journal.pone.0048910