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Cross-Species Functional Genomic Analysis Identifies Resistance Genes of the Histone Deacetylase Inhibitor Valproic Acid

The mechanisms of successful epigenetic reprogramming in cancer are not well characterized as they involve coordinated removal of repressive marks and deposition of activating marks by a large number of histone and DNA modification enzymes. Here, we have used a cross-species functional genomic appro...

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Detalles Bibliográficos
Autores principales: Forthun, Rakel Brendsdal, SenGupta, Tanima, Skjeldam, Hanne Kim, Lindvall, Jessica Margareta, McCormack, Emmet, Gjertsen, Bjørn Tore, Nilsen, Hilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498369/
https://www.ncbi.nlm.nih.gov/pubmed/23155442
http://dx.doi.org/10.1371/journal.pone.0048992