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Cholesterol Side-Chain Cleavage Gene Expression in Theca Cells: Augmented Transcriptional Regulation and mRNA Stability in Polycystic Ovary Syndrome
Hyperandrogenism is characteristic of women with polycystic ovary syndrome (PCOS). Ovarian theca cells isolated from PCOS follicles and maintained in long-term culture produce elevated levels of progestins and androgens compared to normal theca cells. Augmented steroid production in PCOS theca cells...
Autores principales: | Wickenheisser, Jessica K., Biegler, Jessica M., Nelson-DeGrave, Velen L., Legro, Richard S., Strauss, Jerome F., McAllister, Jan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498373/ https://www.ncbi.nlm.nih.gov/pubmed/23155436 http://dx.doi.org/10.1371/journal.pone.0048963 |
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