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Isolated Toll-like Receptor Transmembrane Domains Are Capable of Oligomerization

Toll-like receptors (TLRs) act as the first line of defense against bacterial and viral pathogens by initiating critical defense signals upon dimer activation. The contribution of the transmembrane domain in the dimerization and signaling process has heretofore been overlooked in favor of the extrac...

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Detalles Bibliográficos
Autores principales:	Godfroy, James I., Roostan, Mohammad, Moroz, Yurii S., Korendovych, Ivan V., Yin, Hang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498381/ https://www.ncbi.nlm.nih.gov/pubmed/23155421 http://dx.doi.org/10.1371/journal.pone.0048875

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