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Structural insights into the specific anti-HIV property of actinohivin: structure of its complex with the α(1–2)mannobiose moiety of gp120

Actinohivin (AH) is an actinomycete lectin with a potent specific anti-HIV activity. In order to clarify the structural evidence for its specific binding to the α(1–2)mannobiose (MB) moiety of the D1 chains of high-mannose-type glycans (HMTGs) attached to HIV-1 gp120, the crystal structure of AH in...

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Detalles Bibliográficos
Autores principales:	Hoque, M. Mominul, Suzuki, Kaoru, Tsunoda, Masaru, Jiang, Jiandong, Zhang, Fang, Takahashi, Atsushi, Ohbayashi, Naomi, Zhang, Xiaoxue, Tanaka, Haruo, Ōmura, Satoshi, Takénaka, Akio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2012
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498932/ https://www.ncbi.nlm.nih.gov/pubmed/23151632 http://dx.doi.org/10.1107/S0907444912040498

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