Cargando…
Comparative study between Levobupivacaine and Bupivacaine for hernia surgery in the elderly
BACKGROUND: The inguinal hernia is one of the most common diseases in the elderly. Treatment of this type of pathology is exclusively surgical and relies almost always on the use of local anesthesia. While in the past hernia surgery was carried out mainly by general anesthesia, in recent years there...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499198/ https://www.ncbi.nlm.nih.gov/pubmed/23173755 http://dx.doi.org/10.1186/1471-2482-12-S1-S12 |
_version_ | 1782249916093956096 |
---|---|
author | Compagna, Rita Vigliotti, Gabriele Coretti, Guido Amato, Maurizio Aprea, Giovanni Puzziello, Alessandro Militello, Carmelo Iacono, Fabrizio Prezioso, Domenico Amato, Bruno |
author_facet | Compagna, Rita Vigliotti, Gabriele Coretti, Guido Amato, Maurizio Aprea, Giovanni Puzziello, Alessandro Militello, Carmelo Iacono, Fabrizio Prezioso, Domenico Amato, Bruno |
author_sort | Compagna, Rita |
collection | PubMed |
description | BACKGROUND: The inguinal hernia is one of the most common diseases in the elderly. Treatment of this type of pathology is exclusively surgical and relies almost always on the use of local anesthesia. While in the past hernia surgery was carried out mainly by general anesthesia, in recent years there has been growing emphasis on the role of local anesthesia. METHODS: The aim of our study was to compare intra-and postoperative analgesia obtained by the use of levobupivacaine compared with that of bupivacaine. Bupivacaine is one of the main local anesthetics used in the intervention of inguinal hernioplasty. Levobupivacaine is an enantiomer of racemic bupivacaine with less cardiotoxicity and neurotoxicity. The study was conducted from April 2010 to May 2012. We collected data of forty male patients, aged between 73 and 85 years, who underwent inguinal hernioplasty with local anesthesia for the first time. RESULTS: Minimal pain is the same in both groups. Mild pain was more frequent in the group who used bupivacaine, moderate pain was slightly more frequent in the group who used levobupivacaine, and the same for intense pain. It is therefore evident how Bupivacaine is slightly less preferred after four and twenty four hours, while the two drugs seem to have the same effect at a distance of twelve and forty-eight hours. Bupivacaine shows a significantly higher number of complications, as already demonstrated by previous studies. The request for an analgesic was slightly higher in patients receiving levobupivacaine. CONCLUSIONS: After considering all these elements, we can conclude that the clinical efficacy of levobupivacaine and racemic bupivacaine are essentially similar, when used under local intervention of inguinal hernioplasty. |
format | Online Article Text |
id | pubmed-3499198 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-34991982012-11-20 Comparative study between Levobupivacaine and Bupivacaine for hernia surgery in the elderly Compagna, Rita Vigliotti, Gabriele Coretti, Guido Amato, Maurizio Aprea, Giovanni Puzziello, Alessandro Militello, Carmelo Iacono, Fabrizio Prezioso, Domenico Amato, Bruno BMC Surg Research Article BACKGROUND: The inguinal hernia is one of the most common diseases in the elderly. Treatment of this type of pathology is exclusively surgical and relies almost always on the use of local anesthesia. While in the past hernia surgery was carried out mainly by general anesthesia, in recent years there has been growing emphasis on the role of local anesthesia. METHODS: The aim of our study was to compare intra-and postoperative analgesia obtained by the use of levobupivacaine compared with that of bupivacaine. Bupivacaine is one of the main local anesthetics used in the intervention of inguinal hernioplasty. Levobupivacaine is an enantiomer of racemic bupivacaine with less cardiotoxicity and neurotoxicity. The study was conducted from April 2010 to May 2012. We collected data of forty male patients, aged between 73 and 85 years, who underwent inguinal hernioplasty with local anesthesia for the first time. RESULTS: Minimal pain is the same in both groups. Mild pain was more frequent in the group who used bupivacaine, moderate pain was slightly more frequent in the group who used levobupivacaine, and the same for intense pain. It is therefore evident how Bupivacaine is slightly less preferred after four and twenty four hours, while the two drugs seem to have the same effect at a distance of twelve and forty-eight hours. Bupivacaine shows a significantly higher number of complications, as already demonstrated by previous studies. The request for an analgesic was slightly higher in patients receiving levobupivacaine. CONCLUSIONS: After considering all these elements, we can conclude that the clinical efficacy of levobupivacaine and racemic bupivacaine are essentially similar, when used under local intervention of inguinal hernioplasty. BioMed Central 2012-11-15 /pmc/articles/PMC3499198/ /pubmed/23173755 http://dx.doi.org/10.1186/1471-2482-12-S1-S12 Text en Copyright ©2012 Compagna et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Compagna, Rita Vigliotti, Gabriele Coretti, Guido Amato, Maurizio Aprea, Giovanni Puzziello, Alessandro Militello, Carmelo Iacono, Fabrizio Prezioso, Domenico Amato, Bruno Comparative study between Levobupivacaine and Bupivacaine for hernia surgery in the elderly |
title | Comparative study between Levobupivacaine and Bupivacaine for hernia surgery in the elderly |
title_full | Comparative study between Levobupivacaine and Bupivacaine for hernia surgery in the elderly |
title_fullStr | Comparative study between Levobupivacaine and Bupivacaine for hernia surgery in the elderly |
title_full_unstemmed | Comparative study between Levobupivacaine and Bupivacaine for hernia surgery in the elderly |
title_short | Comparative study between Levobupivacaine and Bupivacaine for hernia surgery in the elderly |
title_sort | comparative study between levobupivacaine and bupivacaine for hernia surgery in the elderly |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499198/ https://www.ncbi.nlm.nih.gov/pubmed/23173755 http://dx.doi.org/10.1186/1471-2482-12-S1-S12 |
work_keys_str_mv | AT compagnarita comparativestudybetweenlevobupivacaineandbupivacaineforherniasurgeryintheelderly AT vigliottigabriele comparativestudybetweenlevobupivacaineandbupivacaineforherniasurgeryintheelderly AT corettiguido comparativestudybetweenlevobupivacaineandbupivacaineforherniasurgeryintheelderly AT amatomaurizio comparativestudybetweenlevobupivacaineandbupivacaineforherniasurgeryintheelderly AT apreagiovanni comparativestudybetweenlevobupivacaineandbupivacaineforherniasurgeryintheelderly AT puzzielloalessandro comparativestudybetweenlevobupivacaineandbupivacaineforherniasurgeryintheelderly AT militellocarmelo comparativestudybetweenlevobupivacaineandbupivacaineforherniasurgeryintheelderly AT iaconofabrizio comparativestudybetweenlevobupivacaineandbupivacaineforherniasurgeryintheelderly AT preziosodomenico comparativestudybetweenlevobupivacaineandbupivacaineforherniasurgeryintheelderly AT amatobruno comparativestudybetweenlevobupivacaineandbupivacaineforherniasurgeryintheelderly |