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Agglomerates of aberrant DNA methylation are associated with toxicant-induced malignant transformation
Epigenetic dysfunction is a known contributor in carcinogenesis, and is emerging as a mechanism involved in toxicant-induced malignant transformation for environmental carcinogens such as arsenicals or cadmium. In addition to aberrant DNA methylation of single genes, another manifestation of epigene...
Autores principales: | Severson, Paul L., Tokar, Erik J., Vrba, Lukas, Waalkes, Michael P., Futscher, Bernard W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499325/ https://www.ncbi.nlm.nih.gov/pubmed/22976526 http://dx.doi.org/10.4161/epi.22163 |
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