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Subtype- and antigenic site-specific differences in biophysical influences on evolution of influenza virus hemagglutinin

BACKGROUND: Influenza virus undergoes rapid evolution by both antigenic shift and antigenic drift. Antibodies, particularly those binding near the receptor-binding site of hemagglutinin (HA) or the neuraminidase (NA) active site, are thought to be the primary defense against influenza infection, and...

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Detalles Bibliográficos
Autor principal:	Stray, Stephen J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499391/ https://www.ncbi.nlm.nih.gov/pubmed/22569196 http://dx.doi.org/10.1186/1743-422X-9-91

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