Fas-deficient mice have impaired alveolar neutrophil recruitment and decreased expression of anti-KC autoantibody:KC complexes in a model of acute lung injury

BACKGROUND: Exposure to mechanical ventilation enhances lung injury in response to various stimuli, such as bacterial endotoxin (LPS). The Fas/FasL system is a receptor ligand system that has dual pro-apoptotic and pro-inflammatory functions and has been implicated in the pathogenesis of lung injury...

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Detalles Bibliográficos
Autores principales: Gil, Sucheol, Farnand, Alex W, Altemeier, William A, Gill, Sean E, Kurdowska, Anna, Krupa, Agnieszka, Florence, Jon M, Matute-Bello, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499442/
https://www.ncbi.nlm.nih.gov/pubmed/23043753
http://dx.doi.org/10.1186/1465-9921-13-91

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