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Function Annotation of Hepatic Retinoid x Receptor α Based on Genome-Wide DNA Binding and Transcriptome Profiling

BACKGROUND: Retinoid x receptor α (RXRα) is abundantly expressed in the liver and is essential for the function of other nuclear receptors. Using chromatin immunoprecipitation sequencing and mRNA profiling data generated from wild type and RXRα-null mouse livers, the current study identifies the bon...

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Detalles Bibliográficos
Autores principales: Zhan, Qi, Fang, Yaping, He, Yuqi, Liu, Hui-Xin, Fang, Jianwen, Wan, Yu-Jui Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499475/
https://www.ncbi.nlm.nih.gov/pubmed/23166811
http://dx.doi.org/10.1371/journal.pone.0050013