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Clinical Presentation of Atopic Dermatitis by Filaggrin Gene Mutation Status during the First 7 Years of Life in a Prospective Cohort Study
BACKGROUND: Filaggrin null mutations result in impaired skin barrier functions, increase the risk of early onset atopic dermatitis and lead to a more severe and chronic disease. We aimed to characterize the clinical presentation and course of atopic dermatitis associated with filaggrin mutations wit...
Autores principales: | Carson, Charlotte Giwercman, Rasmussen, Morten Arendt, Thyssen, Jacob P., Menné, Torkil, Bisgaard, Hans |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499508/ https://www.ncbi.nlm.nih.gov/pubmed/23166590 http://dx.doi.org/10.1371/journal.pone.0048678 |
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