Therapeutic Helminth Infection of Macaques with Idiopathic Chronic Diarrhea Alters the Inflammatory Signature and Mucosal Microbiota of the Colon

Idiopathic chronic diarrhea (ICD) is a leading cause of morbidity amongst rhesus monkeys kept in captivity. Here, we show that exposure of affected animals to the whipworm Trichuris trichiura led to clinical improvement in fecal consistency, accompanied by weight gain, in four out of the five treate...

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Detalles Bibliográficos
Autores principales: Broadhurst, Mara Jana, Ardeshir, Amir, Kanwar, Bittoo, Mirpuri, Julie, Gundra, Uma Mahesh, Leung, Jacqueline M., Wiens, Kirsten E., Vujkovic-Cvijin, Ivan, Kim, Charlie C., Yarovinsky, Felix, Lerche, Nicholas W., McCune, Joseph M., Loke, P'ng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499566/
https://www.ncbi.nlm.nih.gov/pubmed/23166490
http://dx.doi.org/10.1371/journal.ppat.1003000

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