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The Capping Domain in RalF Regulates Effector Functions

The Legionella pneumophila effector protein RalF functions as a guanine nucleotide exchange factor (GEF) that activates the host small GTPase protein ADP-ribosylation factor (Arf), and recruits this host protein to the vacuoles in which this pathogen resides. GEF activity is conferred by the Sec7 do...

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Detalles Bibliográficos
Autores principales: Alix, Eric, Chesnel, Laurent, Bowzard, Brad J., Tucker, Aimee M., Delprato, Anna, Cherfils, Jacqueline, Wood, David O., Kahn, Richard A., Roy, Craig R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499574/
https://www.ncbi.nlm.nih.gov/pubmed/23166491
http://dx.doi.org/10.1371/journal.ppat.1003012