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The Capping Domain in RalF Regulates Effector Functions
The Legionella pneumophila effector protein RalF functions as a guanine nucleotide exchange factor (GEF) that activates the host small GTPase protein ADP-ribosylation factor (Arf), and recruits this host protein to the vacuoles in which this pathogen resides. GEF activity is conferred by the Sec7 do...
Autores principales: | Alix, Eric, Chesnel, Laurent, Bowzard, Brad J., Tucker, Aimee M., Delprato, Anna, Cherfils, Jacqueline, Wood, David O., Kahn, Richard A., Roy, Craig R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499574/ https://www.ncbi.nlm.nih.gov/pubmed/23166491 http://dx.doi.org/10.1371/journal.ppat.1003012 |
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