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Sensitivity of Mitochondrial Transcription and Resistance of RNA Polymerase II Dependent Nuclear Transcription to Antiviral Ribonucleosides

Ribonucleoside analogues have potential utility as anti-viral, -parasitic, -bacterial and -cancer agents. However, their clinical applications have been limited by off target effects. Development of antiviral ribonucleosides for treatment of hepatitis C virus (HCV) infection has been hampered by app...

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Detalles Bibliográficos
Autores principales:	Arnold, Jamie J., Sharma, Suresh D., Feng, Joy Y., Ray, Adrian S., Smidansky, Eric D., Kireeva, Maria L., Cho, Aesop, Perry, Jason, Vela, Jennifer E., Park, Yeojin, Xu, Yili, Tian, Yang, Babusis, Darius, Barauskus, Ona, Peterson, Blake R., Gnatt, Averell, Kashlev, Mikhail, Zhong, Weidong, Cameron, Craig E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499576/ https://www.ncbi.nlm.nih.gov/pubmed/23166498 http://dx.doi.org/10.1371/journal.ppat.1003030

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