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Heterotrimeric G-protein Signaling Is Critical to Pathogenic Processes in Entamoeba histolytica
Heterotrimeric G-protein signaling pathways are vital components of physiology, and many are amenable to pharmacologic manipulation. Here, we identify functional heterotrimeric G-protein subunits in Entamoeba histolytica, the causative agent of amoebic colitis. The E. histolytica Gα subunit EhGα1 ex...
Autores principales: | Bosch, Dustin E., Kimple, Adam J., Muller, Robin E., Giguère, Patrick M., Machius, Mischa, Willard, Francis S., Temple, Brenda R. S., Siderovski, David P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499586/ https://www.ncbi.nlm.nih.gov/pubmed/23166501 http://dx.doi.org/10.1371/journal.ppat.1003040 |
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